BDBM385118 US10287267, Compound 274::US10508099, Compound 274::US10556885, Compound 274::US11174244, Compound 274::US11673881, Compound 274

SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)CN3CC[C@@H](F)C3)cc2c1

InChI Key InChIKey=AHVVQOPDAHKCJF-QGZVFWFLSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385118   

TargetProto-oncogene Wnt-1(Homo sapiens (human))
Samumed

US Patent
LigandPNGBDBM385118(US10287267, Compound 274 | US10508099, Compound 27...)
Affinity DataEC50:  3.72E+3nMAssay Description:The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene Wnt-1(Homo sapiens (human))
Samumed

US Patent
LigandPNGBDBM385118(US10287267, Compound 274 | US10508099, Compound 27...)
Affinity DataEC50:  3.72E+3nMAssay Description:SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent